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Glucocorticoid Regulation of SLIT/ROBO Tumour Suppressor Genes in the Ovarian Surface Epithelium and Ovarian Cancer Cells

The three SLIT ligands and their four ROBO receptors have fundamental roles in mammalian development by promoting apoptosis and repulsing aberrant cell migration. SLITs and ROBOs have emerged as candidate tumour suppressor genes whose expression is inhibited in a variety of epithelial tumours. We de...

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Bibliografiske detaljer
Main Authors: Dickinson, Rachel E., Fegan, K. Scott, Ren, Xia, Hillier, Stephen G., Duncan, W. Colin
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3223191/
https://ncbi.nlm.nih.gov/pubmed/22132142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027792
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