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Investigation of intravenous delivery of nanoliposomal topotecan for activity against orthotopic glioblastoma xenografts

Achieving effective treatment outcomes for patients with glioblastoma (GBM) has been impeded by many obstacles, including the pharmacokinetic limitations of antitumor agents, such as topotecan (TPT). Here, we demonstrate that intravenous administration of a novel nanoliposomal formulation of TPT (nL...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Serwer, Laura P., Noble, Charles O., Michaud, Karine, Drummond, Daryl C., Kirpotin, Dmitri B., Ozawa, Tomoko, Prados, Michael D., Park, John W., James, C. David
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Oxford University Press 2011
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3223095/
https://ncbi.nlm.nih.gov/pubmed/21954443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nor139
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