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Phase II and pharmacogenomics study of enzastaurin plus temozolomide during and following radiation therapy in patients with newly diagnosed glioblastoma multiforme and gliosarcoma

This open-label, single-arm, phase II study combined enzastaurin with temozolomide plus radiation therapy (RT) to treat glioblastoma multiforme (GBM) and gliosarcoma. Adults with newly diagnosed disease and Karnofsky performance status (KPS) ≥ 60 were enrolled. Treatment was started within 5 weeks a...

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書誌詳細
主要な著者: Butowski, Nicholas, Chang, Susan M., Lamborn, Kathleen R., Polley, Mei–Yin, Pieper, Russell, Costello, Joseph F., Vandenberg, Scott, Parvataneni, Rupa, Nicole, Angelina, Sneed, Patricia K., Clarke, Jennifer, Hsieh, Emily, Costa, Bruno M., Reis, Rui M., Hristova-Kazmierski, Maria, Nicol, Steven J., Thornton, Donald E., Prados, Michael D.
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3223090/
https://ncbi.nlm.nih.gov/pubmed/21896554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nor130
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