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Phase II Study of Erlotinib Plus Temozolomide During and After Radiation Therapy in Patients With Newly Diagnosed Glioblastoma Multiforme or Gliosarcoma

PURPOSE: This open-label, prospective, single-arm, phase II study combined erlotinib with radiation therapy (XRT) and temozolomide to treat glioblastoma multiforme (GBM) and gliosarcoma. The objectives were to determine efficacy of this treatment as measured by survival and to explore the relationsh...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Prados, Michael D., Chang, Susan M., Butowski, Nicholas, DeBoer, Rebecca, Parvataneni, Rupa, Carliner, Hannah, Kabuubi, Paul, Ayers-Ringler, Jennifer, Rabbitt, Jane, Page, Margaretta, Fedoroff, Anne, Sneed, Penny K., Berger, Mitchel S., McDermott, Michael W., Parsa, Andrew T., Vandenberg, Scott, James, C. David, Lamborn, Kathleen R., Stokoe, David, Haas-Kogan, Daphne A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Clinical Oncology 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2645859/
https://ncbi.nlm.nih.gov/pubmed/19075262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2008.18.9639
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