Phase II Study of Erlotinib Plus Temozolomide During and After Radiation Therapy in Patients With Newly Diagnosed Glioblastoma Multiforme or Gliosarcoma

PURPOSE: This open-label, prospective, single-arm, phase II study combined erlotinib with radiation therapy (XRT) and temozolomide to treat glioblastoma multiforme (GBM) and gliosarcoma. The objectives were to determine efficacy of this treatment as measured by survival and to explore the relationsh...

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Hlavní autoři: Prados, Michael D., Chang, Susan M., Butowski, Nicholas, DeBoer, Rebecca, Parvataneni, Rupa, Carliner, Hannah, Kabuubi, Paul, Ayers-Ringler, Jennifer, Rabbitt, Jane, Page, Margaretta, Fedoroff, Anne, Sneed, Penny K., Berger, Mitchel S., McDermott, Michael W., Parsa, Andrew T., Vandenberg, Scott, James, C. David, Lamborn, Kathleen R., Stokoe, David, Haas-Kogan, Daphne A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Clinical Oncology 2009
Témata:
Original Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2645859/
https://ncbi.nlm.nih.gov/pubmed/19075262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2008.18.9639
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