Phase 1 study of erlotinib HCl alone and combined with temozolomide in patients with stable or recurrent malignant glioma

The purpose of this study was to define the maximum tolerated dose of erlotinib and characterize its pharmacokinetics and safety profile, alone and with temozolomide, with and without enzyme-inducing antiepileptic drugs (EIAEDs), in patients with malignant gliomas. Patients with stable or progressiv...

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Bibliografiske detaljer
Main Authors: Prados, Michael D., Lamborn, Kathleen R., Chang, Susan, Burton, Eric, Butowski, Nicholas, Malec, Mary, Kapadia, Ami, Rabbitt, Jane, Page, Margaretta S., Fedoroff, Ann, Xie, Dong, Kelley, Sean K.
Format: Artigo
Sprog:Inglês
Udgivet: Duke University Press 2006
Fag:
Clinical Investigations
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1871925/
https://ncbi.nlm.nih.gov/pubmed/16443950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1215/S1522851705000451
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