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Activation of PPARα inhibits IGF-I-mediated growth and survival responses in medulloblastoma cell lines
Recent studies suggest a potential role of lipid lowering drugs, fibrates and statins, in anticancer treatment. One candidate for tumor chemoprevention is fenofibrate, which is a potent agonist of peroxisome proliferator activated receptor alpha (PPARα). Our results demonstrate elevated expression o...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3222922/ https://ncbi.nlm.nih.gov/pubmed/18546270 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.23588 |
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