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Activation of PPARα inhibits IGF-I-mediated growth and survival responses in medulloblastoma cell lines

Recent studies suggest a potential role of lipid lowering drugs, fibrates and statins, in anticancer treatment. One candidate for tumor chemoprevention is fenofibrate, which is a potent agonist of peroxisome proliferator activated receptor alpha (PPARα). Our results demonstrate elevated expression o...

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Autors principals: Urbanska, Katarzyna, Pannizzo, Paola, Grabacka, Maja, Croul, Sidney, Del Valle, Luis, Khalili, Kamel, Reiss, Krzysztof
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3222922/
https://ncbi.nlm.nih.gov/pubmed/18546270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.23588
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