IGF-IR in neuroprotection and brain tumors

The IGF-IR is a multifunctional tyrosine kinase receptor involved in several biological processes including cell proliferation, differentiation, DNA repair, and cell survival. In the brain IGF-I plays a critical role during embryonic and early postnatal development. In the mature brain, IGF-I bindin...

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Bibliographic Details
Main Authors: Gualco, Elisa, Wang, Jin Ying, Valle, Luis Del, Urbanska, Katarzyna, Peruzzi, Francesca, Khalili, Kamel, Amini, Shohreh, Reiss, Krzysztof
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679154/
https://ncbi.nlm.nih.gov/pubmed/19273072
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