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Cross-Talk Between T-Ag Presence and pRb Family and p53/p73 Signaling in Mouse and Human Medulloblastoma
The formation and progression of mudulloblastoma (MB) is poorly understood. However, somatic inactivation of pRb/p105, in combination with a somatic or a germ-line TP53 inactivation, leads to MB in a mouse model. Presently, there is no specific evidence of pathway/s alterations for the other two mem...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3222916/ https://ncbi.nlm.nih.gov/pubmed/20336668 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.22525 |
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