An ARL3–UNC119–RP2 GTPase cycle targets myristoylated NPHP3 to the primary cilium

The membrane of the primary cilium is a highly specialized compartment that organizes proteins to achieve spatially ordered signaling. Disrupting ciliary organization leads to diseases called ciliopathies, with phenotypes ranging from retinal degeneration and cystic kidneys to neural tube defects. H...

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Hlavní autoři: Wright, Kevin J., Baye, Lisa M., Olivier-Mason, Anique, Mukhopadhyay, Saikat, Sang, Liyun, Kwong, Mandy, Wang, Weiru, Pretorius, Pamela R., Sheffield, Val C., Sengupta, Piali, Slusarski, Diane C., Jackson, Peter K.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2011
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Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3222901/
https://ncbi.nlm.nih.gov/pubmed/22085962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.173443.111
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