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SirT1 gain-of-function increases energy efficiency and prevents diabetes in mice
In yeast, worms and flies, an extra copy of the gene encoding the Sirtuin Sir2 increases metabolic efficiency, as does administration of polyphenols like resveratrol, thought to act through Sirtuins. But evidence that Sirtuin gain-of-function results in increased metabolic efficiency in mammals is l...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3222897/ https://ncbi.nlm.nih.gov/pubmed/18840364 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2008.08.014 |
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