RNA Interference Improves Myopathic Phenotypes in Mice Over-expressing FSHD Region Gene 1 (FRG1)

Muscular dystrophies, and other diseases of muscle, arise from recessive and dominant gene mutations. Gene replacement strategies may be beneficial for the former, while gene silencing approaches may provide treatment for the latter. In the last two decades, muscle-directed gene therapies were prima...

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Hlavní autoři: Wallace, Lindsay M, Garwick-Coppens, Sara E, Tupler, Rossella, Harper, Scott Q
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2011
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3222519/
https://ncbi.nlm.nih.gov/pubmed/21730972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.118
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