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Autoregulation of the nonsense-mediated mRNA decay pathway in human cells

Nonsense-mediated mRNA decay (NMD) is traditionally portrayed as a quality-control mechanism that degrades mRNAs with truncated open reading frames (ORFs). However, it is meanwhile clear that NMD also contributes to the post-transcriptional gene regulation of numerous physiological mRNAs. To identif...

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Autori principali: Yepiskoposyan, Hasmik, Aeschimann, Florian, Nilsson, Daniel, Okoniewski, Michal, Mühlemann, Oliver
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3222124/
https://ncbi.nlm.nih.gov/pubmed/22028362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.030247.111
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