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Rapamycin Attenuates Airway Hyperreactivity, Goblet Cells, and IgE in Experimental Allergic Asthma

The mammalian target of rapamycin (mTOR) signaling pathway integrates environmental cues, promotes cell growth / differentiation and regulates immune responses. While inhibition of mTOR with rapamycin has potent immunosuppressive activity, mixed effects have been reported in ovalbumin-induced models...

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Hlavní autoři: Mushaben, Elizabeth M., Kramer, Elizabeth L., Brandt, Eric B., Hershey, Gurjit K. Khurana, Le Cras, Timothy D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3221931/
https://ncbi.nlm.nih.gov/pubmed/22021618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102133
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