ロード中...
Mass Spectrometry Based Approach to Study the Kinetics of O(6)-Alkylguanine DNA Alkyltransferase Mediated Repair of O(6)-pyridyloxobutyl-2′-deoxyguanosine Adducts in DNA
O(6)-POB-dG (O(6)-[4-oxo-4-(3-pyridyl)but-1-yl]deoxyguanosine) are promutagenic nucleobase adducts that arise from DNA alkylation by metabolically activated tobacco-specific nitrosamines such as 4-(methylnitrosamino)- 1-(3-pyridyl)-1-butanone (NNK) and N-nitrosonicotine (NNN). If not repaired, O(6)-...
保存先:
| 主要な著者: | , , , , , , |
|---|---|
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
|
| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3221886/ https://ncbi.nlm.nih.gov/pubmed/21913712 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx2002993 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|