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The Signal-Anchor Sequence of CYP2C1 Inserts into the Membrane as a Hairpin Structure
Microsomal cytochrome P450s (CYPs) are anchored to the endoplasmic reticulum membrane by the N-terminal signal-anchor sequence which is predicted to insert into the membrane as a type 1 transmembrane helix with a luminally located N-terminus. We have mapped amino acids of the CYP2C1 signal-anchor, f...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3221809/ https://ncbi.nlm.nih.gov/pubmed/22040732 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2011.10.082 |
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