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CYP2C8 Exists as a Dimer in Natural Membranes

CYP2C8 with a modified N-terminal sequence (2C8H) crystallizes as a dimer, but it is not known whether native CYP2C8 exists as a dimer in natural membranes. We have examined the organization of 2C8H and CYP2C8 expressed in bacterial membranes and mammalian endoplasmic reticulum membranes, respective...

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Hlavní autoři: Hu, Gang, Johnson, Eric F., Kemper, Byron
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Pharmacology and Experimental Therapeutics 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2967391/
https://ncbi.nlm.nih.gov/pubmed/20699412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.110.034942
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