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PROTEASOME INHIBITION COMPROMISES DIRECT RETENTION OF CYTOCHROME P450 2C2 IN THE ENDOPLASMIC RETICULUM
To determine whether protein degradation plays a role in the endoplasmic reticulum (ER) retention of cytochromes P450, the effects of proteasomal inhibitors on the expression and distribution of green fluorescent protein chimeras of CYP2C2 and related proteins was examined. In transfected cells, exp...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2008
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2632573/ https://ncbi.nlm.nih.gov/pubmed/18755184 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2008.08.003 |
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