A gene expression signature from human breast cancer cells with acquired hormone independence identifies MYC as a mediator of antiestrogen resistance

PURPOSE: Although most patients with estrogen receptor α (ER)-positive breast cancer initially respond to endocrine therapy, many ultimately develop resistance to antiestrogens. However, mechanisms of antiestrogen resistance and biomarkers predictive of such resistance are underdeveloped. EXPERIMENT...

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Autori principali: Miller, Todd W., Balko, Justin M., Ghazoui, Zara, Dunbier, Anita, Anderson, Helen, Dowsett, Mitch, González-Angulo, Ana M., Mills, Gordon B., Miller, William R., Wu, Huiyun, Shyr, Yu, Arteaga, Carlos L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3221728/
https://ncbi.nlm.nih.gov/pubmed/21346144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-2567
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