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Phosphatidylinositol 3-Kinase and Antiestrogen Resistance in Breast Cancer

Although antiestrogen therapies targeting estrogen receptor (ER) α signaling prevent disease recurrence in the majority of patients with hormone-dependent breast cancer, a significant fraction of patients exhibit de novo or acquired resistance. Currently, the only accepted mechanism linked with endo...

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Autori principali: Miller, Todd W., Balko, Justin M., Arteaga, Carlos L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Clinical Oncology 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3221526/
https://ncbi.nlm.nih.gov/pubmed/22010023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2010.34.4879
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