DNA Methylation Profiles of Primary Colorectal Carcinoma and Matched Liver Metastasis

BACKGROUND: The contribution of DNA methylation to the metastatic process in colorectal cancers (CRCs) is unclear. METHODS: We evaluated the methylation status of 13 genes (MINT1, MINT2, MINT31, MLH1, p16, p14, TIMP3, CDH1, CDH13, THBS1, MGMT, HPP1 and ERα) by bisulfite-pyrosequencing in 79 CRCs com...

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Detalhes bibliográficos
Main Authors: Konishi, Kazuo, Watanabe, Yoshiyuki, Shen, Lanlan, Guo, Yi, Castoro, Ryan J., Kondo, Kimie, Chung, Woonbok, Ahmed, Saira, Jelinek, Jaroslav, Boumber, Yanis A., Estecio, Marcos R., Maegawa, Shinji, Kondo, Yutaka, Itoh, Fumio, Imawari, Michio, Hamilton, Stanley R., Issa, Jean-Pierre J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3221680/
https://ncbi.nlm.nih.gov/pubmed/22132162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027889
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