Concordant DNA Methylation in Synchronous Colorectal Carcinomas

Epigenetic changes have been proposed as mediators of the field defect in colorectal carcinogenesis, which has implications for risk assessment and cancer prevention. As a test of this hypothesis, we evaluated the methylation status of eight genes (MINT1, 2, 31, MLH1, p16, p14, MGMT, and ESR1), as w...

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Hlavní autoři: Konishi, Kazuo, Shen, Lanlan, Jelinek, Jaroslav, Watanabe, Yoshiyuki, Ahmed, Saira, Kaneko, Kazuhiro, Kogo, Mari, Takano, Toshihumi, Imawari, Michio, Hamilton, Stanley R., Issa, Jean-Pierre J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3544187/
https://ncbi.nlm.nih.gov/pubmed/19737982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-09-0054
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