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Genetic or nutritional disorders in homocysteine or folate metabolism increase protein N-homocysteinylation in mice
Genetic disorders of homocysteine (Hcy) or folate metabolism or high-methionine diets elevate plasma Hcy and its atherogenic metabolite Hcy-thiolactone. In humans, severe hyperhomocysteinemia due to genetic alterations in cystathionine β-synthase (Cbs) or methylenetetrahydrofolate reductase (Mthfr)...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Federation of American Societies for Experimental Biology
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3221610/ https://ncbi.nlm.nih.gov/pubmed/19204075 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.08-127548 |
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