Anti‐N‐homocysteine‐protein autoantibodies are associated with impaired cognition

INTRODUCTION: Elevated homocysteine (Hcy) and related metabolites accelerate Alzheimer's disease. Hcy‐lowering B vitamins slow brain atrophy/cognitive decline in mild cognitive impairment (MCI). Modification with Hcy‐thiolactone generates auto‐immunogenic N‐Hcy‐protein. We tested a hypothesis t...

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Publicat a:Alzheimers Dement (N Y)
Autors principals: Włoczkowska, Olga, Perła‐Kaján, Joanna, Smith, A. David, de Jager, Celeste, Refsum, Helga, Jakubowski, Hieronim
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2021
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Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8010366/
https://ncbi.nlm.nih.gov/pubmed/33816764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/trc2.12159
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