SITE-SPECIFIC LYS-63-LINKED TUMOR NECROSIS FACTOR RECEPTOR-ASSOCIATED FACTOR 6 AUTO-UBIQUITINATION IS A CRITICAL DETERMINANT OF IKK ACTIVATION

Tumor necrosis factor (TNF) receptor-associated factor 6 (TRAF6) is a key mediator in proximal signaling of the interleukin-1/Toll-like receptor and the TNF receptor superfamily. Analysis of TRAF6-deficient mice revealed a fundamental role of TRAF6 in osteoclastogenesis; however, the molecular mecha...

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Bibliografiska uppgifter
Huvudupphovsmän: Lamothe, Betty, Besse, Arnaud, Campos, Alejandro D., Webster, William K., Wu, Hao, Darnay, Bryant G.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2006
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3221607/
https://ncbi.nlm.nih.gov/pubmed/17135271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M609503200
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