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SITE-SPECIFIC LYS-63-LINKED TUMOR NECROSIS FACTOR RECEPTOR-ASSOCIATED FACTOR 6 AUTO-UBIQUITINATION IS A CRITICAL DETERMINANT OF IKK ACTIVATION
Tumor necrosis factor (TNF) receptor-associated factor 6 (TRAF6) is a key mediator in proximal signaling of the interleukin-1/Toll-like receptor and the TNF receptor superfamily. Analysis of TRAF6-deficient mice revealed a fundamental role of TRAF6 in osteoclastogenesis; however, the molecular mecha...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3221607/ https://ncbi.nlm.nih.gov/pubmed/17135271 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M609503200 |
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