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Capturing Alzheimer's disease genomes with induced pluripotent stem cells: prospects and challenges

A crucial limitation to our understanding of Alzheimer's disease (AD) is the inability to test hypotheses on live, patient-specific neurons. Patient autopsies are limited in supply and only reveal endpoints of disease. Rodent models harboring familial AD mutations lack important pathologies, an...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Israel, Mason A, Goldstein, Lawrence SB
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3221547/
https://ncbi.nlm.nih.gov/pubmed/21867573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm265
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