Human tumor cell lines with EGF receptor gene amplification in the absence of aberrant sized mRNAs.

A survey of human tumor cell lines for increased PDGF or EGF receptors identified 5 lines which bind from 6 to 13 times more EGF than normal human fibroblasts. Immunoprecipitation analysis links the elevated binding activity to increased quantities of the EGF receptor protein. EGF receptor gene ampl...

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Bibliografiske detaljer
Main Authors: King, C R, Kraus, M H, Williams, L T, Merlino, G T, Pastan, I H, Aaronson, S A
Format: Artigo
Sprog:Inglês
Udgivet: 1985
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC322146/
https://ncbi.nlm.nih.gov/pubmed/3001641
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