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Human tumor cell lines with EGF receptor gene amplification in the absence of aberrant sized mRNAs.
A survey of human tumor cell lines for increased PDGF or EGF receptors identified 5 lines which bind from 6 to 13 times more EGF than normal human fibroblasts. Immunoprecipitation analysis links the elevated binding activity to increased quantities of the EGF receptor protein. EGF receptor gene ampl...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
1985
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| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC322146/ https://ncbi.nlm.nih.gov/pubmed/3001641 |
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