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Targeting of Aberrant mRNAs to Cytoplasmic Processing Bodies
In eukaryotes, a specialized pathway of mRNA degradation termed nonsense-mediated decay (NMD) functions in mRNA quality control by recognizing and degrading mRNAs with aberrant termination codons. We demonstrate that NMD in yeast targets premature termination codon (PTC)-containing mRNA to P-bodies....
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1858659/ https://ncbi.nlm.nih.gov/pubmed/16777600 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2006.04.037 |
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