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Decapping and Decay of Messenger RNA Occur in Cytoplasmic Processing Bodies
A major pathway of eukaryotic messenger RNA (mRNA) turnover begins with deadenylation, followed by decapping and 5′ to 3′ exonucleolytic decay. We provide evidence that mRNA decapping and 5′ to 3′ degradation occur in discrete cytoplasmic foci in yeast, which we call processing bodies (P bodies). Fi...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2003
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1876714/ https://ncbi.nlm.nih.gov/pubmed/12730603 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1082320 |
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