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Synthesis enables a structural revision of the Mycobacterium tuberculosis-produced diterpene, edaxadiene()

A stereodivergent synthesis of the [3.3.1] bicyclic core of edaxadiene was completed utilizing a key intramolecular oxidative ketone allylation. Significant discrepancies between the spectroscopic data obtained for the synthetic construct and the natural isolate raised questions about the structural...

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Detalhes bibliográficos
Main Authors: Spangler, Jillian E., Carson, Cheryl A., Sorensen, Erik J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3221386/
https://ncbi.nlm.nih.gov/pubmed/22114734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C0SC00284D
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