A Common Variant in the Patatin-Like Phospholipase 3 Gene (PNPLA3) Is Associated with Fatty Liver Disease in Obese Children and Adolescents

The genetic factors associated with susceptibility to nonalcoholic fatty liver disease (NAFLD) in pediatric obesity remain largely unknown. Recently, a nonsynonymous single-nucleotide polymorphism (rs738409), in the patatin-like phospholipase 3 gene (PNPLA3) has been associated with hepatic steatosi...

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Autori principali: Santoro, Nicola, Kursawe, Romy, D’Adamo, Ebe, Dykas, Daniel J., Zhang, Clarence K., Bale, Allen E., Calí, Anna M., Narayan, Deepak, Shaw, Melissa M., Pierpont, Bridget, Savoye, Mary, Lartaud, Derek, Eldrich, Samuel, Cushman, Samuel W., Zhao, Hongyu, Shulman, Gerald I., Caprio, Sonia
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3221304/
https://ncbi.nlm.nih.gov/pubmed/20803499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.23832
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