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An NMR study of A-T base pair opening rates in oligonucleotides. Influence of sequence and of adenine methylation.

We report relaxation time measurements by semi-selective and totally selective NMR techniques on the thymidine imino protons of d(GGATATCC) and d(GGm6ATATCC). For these oligonucleotides helix fraying, rather than single base pair opening, is the major exchange mechanism even 25 degrees C below the T...

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Sábháilte in:
Sonraí bibleagrafaíochta
Foilsithe in:Nucleic Acids Res
Príomhchruthaitheoirí: Quignard, E, Téoule, R, Guy, A, Fazakerley, G V
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: Oxford University Press 1985
Rochtain ar líne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC322089/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4069998/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/13.21.7829
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