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Proton NMR study and conformational analysis of d(CGT), d(TCG) and d(CGTCG) in aqueous solution. The effect of a dangling thymidine and of a thymidine mismatch on DNA mini-duplexes.

Proton NMR studies of d(CGT), d(TCG) and d(CGTCG) were carried out at 300 and 500 MHz. The temperature and concentration dependence of the chemical shifts of various resonances indicates duplex formation only in the cases of d(TCG) and d(CGTCG). It is concluded that d(TCG) forms a mini-duplex stabil...

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Main Authors: Mellema, J R, van der Woerd, R, van der Marel, G A, van Boom, J H, Altona, C
格式: Artigo
語言:Inglês
出版: 1984
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC318900/
https://ncbi.nlm.nih.gov/pubmed/6739297
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