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An NMR study of A-T base pair opening rates in oligonucleotides. Influence of sequence and of adenine methylation.
We report relaxation time measurements by semi-selective and totally selective NMR techniques on the thymidine imino protons of d(GGATATCC) and d(GGm6ATATCC). For these oligonucleotides helix fraying, rather than single base pair opening, is the major exchange mechanism even 25 degrees C below the T...
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| Published in: | Nucleic Acids Res |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
1985
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| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC322089/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4069998/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/13.21.7829 |
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