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14-3-3σ and p63 play opposing roles in epidermal tumorigenesis
14-3-3σ plays a regulatory role in epidermal epithelial differentiation and loss of 14-3-3σ leads to increased proliferation and impaired differentiation. A tumor suppressor function for 14-3-3σ has been proposed based on the fact that some epithelial-derived tumors lose 14-3-3σ expression. p63, a p...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3220605/ https://ncbi.nlm.nih.gov/pubmed/21926108 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgr207 |
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