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14-3-3σ regulates keratinocyte proliferation and differentiation by modulating Yap1 cellular localization
The homozygous repeated epilation (Er/Er) mouse mutant of the gene encoding 14-3-3σ displays an epidermal phenotype characterized by hyperproliferative keratinocytes and undifferentiated epidermis. Heterozygous Er/+ mice develop spontaneous skin tumors and are highly sensitive to tumor-promoting DMB...
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| Publicado no: | J Invest Dermatol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4430425/ https://ncbi.nlm.nih.gov/pubmed/25668240 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2015.42 |
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