CRM1 Protein-mediated Regulation of Nuclear Clusterin (nCLU), an Ionizing Radiation-stimulated, Bax-dependent Pro-death Factor

Expression of the clusterin (CLU) gene results in the synthesis of a conventional secretory isoform set (pre- and mature secretory clusterin proteins, psCLU/sCLU), as well as another set of intracellular isoforms, appearing in the cytoplasm (pre-nuclear CLU, pnCLU) and in the nucleus as an ∼55-kDa m...

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Hlavní autoři: Leskov, Konstantin S., Araki, Shinako, Lavik, John-Paul, Gomez, Jose A., Gama, Vivian, Gonos, Efstathios S., Trougakos, Ioannis P., Matsuyama, Shigemi, Boothman, David A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2011
Témata:
Cell Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3220538/
https://ncbi.nlm.nih.gov/pubmed/21953454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.252957
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