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Low dose IR-induced IGF-1-sCLU expression: a p53-repressed expression cascade that interferes with TGFβ1 signaling to confer a pro-survival bystander effect

Inadvertent mammalian tissue exposures to low doses of ionizing radiation (IR) after radiation accidents, remediation of radioactive-contaminated areas, space travel, or a dirty bomb represents an interesting trauma to an organism. Possible low dose IR-induced bystander effects could impact our eval...

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Detalhes bibliográficos
Main Authors: Klokov, Dmitry, Leskov, Konstantin, Araki, Shinako, Zou, Yonglong, Goetz, Eva M., Luo, Xiuquan, Willson, David, Boothman, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3371099/
https://ncbi.nlm.nih.gov/pubmed/22391565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.64
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