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Involvement of ATP-sensitive Potassium (K(ATP)) Channels in the Loss of Beta-cell Function Induced by Human Islet Amyloid Polypeptide
Islet amyloid polypeptide (IAPP) is a major component of amyloid deposition in pancreatic islets of patients with type 2 diabetes. It is known that IAPP can inhibit glucose-stimulated insulin secretion; however, the mechanisms of action have not yet been established. In the present work, using a rat...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3220453/ https://ncbi.nlm.nih.gov/pubmed/21984830 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.232801 |
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