Dissociation of diabetes and obesity in mice lacking orphan nuclear receptor small heterodimer partner

Mixed background SHP(−/−) mice are resistant to diet-induced obesity due to increased energy expenditure caused by enhanced PGC-1α expression in brown adipocytes. However, congenic SHP(−/−) mice on the C57BL/6 background showed normal expression of PGC-1α and other genes involved in brown adipose ti...

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Bibliografiske detaljer
Main Authors: Park, Young Joo, Kim, Seong Chul, Kim, Jeehee, Anakk, Sayeepriyadarshini, Lee, Jae Man, Tseng, Hsiu-Ting, Yechoor, Vijay, Park, Junchol, Choi, June-Seek, Jang, Hak Chul, Lee, Ki-Up, Novak, Colleen M., Moore, David D., Lee, Yoon Kwang
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Biochemistry and Molecular Biology 2011
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3220290/
https://ncbi.nlm.nih.gov/pubmed/21949050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M016048
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