Modulated contact frequencies at gene-rich loci support a statistical helix model for mammalian chromatin organization

BACKGROUND: Despite its critical role for mammalian gene regulation, the basic structural landscape of chromatin in living cells remains largely unknown within chromosomal territories below the megabase scale. RESULTS: Here, using the 3C-qPCR method, we investigate contact frequencies at high resolu...

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Autori principali: Court, Franck, Miro, Julie, Braem, Caroline, Lelay-Taha, Marie-Noëlle, Brisebarre, Audrey, Atger, Florian, Gostan, Thierry, Weber, Michaël, Cathala, Guy, Forné, Thierry
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2011
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219965/
https://ncbi.nlm.nih.gov/pubmed/21569291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2011-12-5-r42
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