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Distinct polymer physics principles govern chromatin dynamics in mouse and Drosophila topological domains
BACKGROUND: In higher eukaryotes, the genome is partitioned into large "Topologically Associating Domains" (TADs) in which the chromatin displays favoured long-range contacts. While a crumpled/fractal globule organization has received experimental supports at higher-order levels, the organ...
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Publicado no: | BMC Genomics |
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Main Authors: | , , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4536789/ https://ncbi.nlm.nih.gov/pubmed/26271925 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-015-1786-8 |
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