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Distinct polymer physics principles govern chromatin dynamics in mouse and Drosophila topological domains

BACKGROUND: In higher eukaryotes, the genome is partitioned into large "Topologically Associating Domains" (TADs) in which the chromatin displays favoured long-range contacts. While a crumpled/fractal globule organization has received experimental supports at higher-order levels, the organ...

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Bibliographic Details
Published in:BMC Genomics
Main Authors: Ea, Vuthy, Sexton, Tom, Gostan, Thierry, Herviou, Laurie, Baudement, Marie-Odile, Zhang, Yunzhe, Berlivet, Soizik, Le Lay-Taha, Marie-Noëlle, Cathala, Guy, Lesne, Annick, Victor, Jean-Marc, Fan, Yuhong, Cavalli, Giacomo, Forné, Thierry
Format: Artigo
Language:Inglês
Published: BioMed Central 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4536789/
https://ncbi.nlm.nih.gov/pubmed/26271925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-015-1786-8
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