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Construction and Analysis of an Integrated Regulatory Network Derived from High-Throughput Sequencing Data

We present a network framework for analyzing multi-level regulation in higher eukaryotes based on systematic integration of various high-throughput datasets. The network, namely the integrated regulatory network, consists of three major types of regulation: TF→gene, TF→miRNA and miRNA→gene. We ident...

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Autors principals: Cheng, Chao, Yan, Koon-Kiu, Hwang, Woochang, Qian, Jiang, Bhardwaj, Nitin, Rozowsky, Joel, Lu, Zhi John, Niu, Wei, Alves, Pedro, Kato, Masaomi, Snyder, Michael, Gerstein, Mark
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219617/
https://ncbi.nlm.nih.gov/pubmed/22125477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002190
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