Elucidation of the mechanism of selective inhibition of mammalian DNA polymerase alpha by 2-butylanilinopurines: development and characterization of 2-(p-n-butylanilino)adenine and its deoxyribonucleotides.

2-(p-n-Butylanilino)adenine (BuAA), an homolog of the DNA polymerase alpha (pol alpha)-specific inhibitor, N2-(p-n-butylphenyl)guanine (BuPG), was transformed to its 2'-deoxyribonucleoside, BuAdA, and the corresponding 2'-deoxyribonucleoside 5'-phosphates, BuAdAMP, BuAdADP, and BuAdAT...

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Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Khan, N N, Wright, G E, Dudycz, L W, Brown, N C
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 1985
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC321956/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3931053/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/13.17.6331
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