Impact of Epidermal Growth Factor Receptor and KRAS Mutations on Clinical Outcomes in Previously Untreated Non–Small Cell Lung Cancer Patients: Results of an Online Tumor Registry of Clinical Trials

PURPOSE: The impact of epidermal growth factor receptor (EGFR) and KRAS genotypes on outcomes with erlotinib or gefitinib therapy continues to be debated. This study combines patient data from five trials in predominantly Western populations to assess the impact of EGFR and KRAS mutations on first-l...

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Detalhes bibliográficos
Main Authors: Jackman, David M., Miller, Vincent A., Cioffredi, Leigh-Anne, Yeap, Beow Y., Jänne, Pasi A., Riely, Gregory J., Ruiz, Marielle Gallegos, Giaccone, Giuseppe, Sequist, Lecia V., Johnson, Bruce E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219530/
https://ncbi.nlm.nih.gov/pubmed/19671843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-09-0888
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