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Activation of factor VII-activating protease in human inflammation: a sensor for cell death

INTRODUCTION: Cell death is a central event in the pathogenesis of sepsis and is reflected by circulating nucleosomes. Circulating nucleosomes were suggested to play an important role in inflammation and were demonstrated to correlate with severity and outcome in sepsis patients. We recently showed...

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Detalhes bibliográficos
Main Authors: Stephan, Femke, Hazelzet, Jan A, Bulder, Ingrid, Boermeester, Marja A, van Till, JW Olivier, van der Poll, Tom, Wuillemin, Walter A, Aarden, Lucien A, Zeerleder, Sacha
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219388/
https://ncbi.nlm.nih.gov/pubmed/21466697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc10131
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