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Increased Nucleosomes and Neutrophil Activation Link to Disease Progression in Patients with Scrub Typhus but Not Murine Typhus in Laos

Cell-mediated immunity is essential in protection against rickettsial illnesses, but the role of neutrophils in these intracellular vasculotropic infections remains unclear. This study analyzed the plasma levels of nucleosomes, FSAP-activation (nucleosome-releasing factor), and neutrophil activation...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Paris, Daniel H., Stephan, Femke, Bulder, Ingrid, Wouters, Diana, van der Poll, Tom, Newton, Paul N., Day, Nicholas P. J., Zeerleder, Sacha
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4552835/
https://ncbi.nlm.nih.gov/pubmed/26317419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0003990
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