Nkx2.2 repressor complex regulates islet β-cell specification and prevents β-to-α-cell reprogramming

Regulation of cell differentiation programs requires complex interactions between transcriptional and epigenetic networks. Elucidating the principal molecular events responsible for the establishment and maintenance of cell fate identities will provide important insights into how cell lineages are s...

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Main Authors: Papizan, James B., Singer, Ruth A., Tschen, Shuen-Ing, Dhawan, Sangeeta, Friel, Jessica M., Hipkens, Susan B., Magnuson, Mark A., Bhushan, Anil, Sussel, Lori
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2011
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219233/
https://ncbi.nlm.nih.gov/pubmed/22056672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.173039.111
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