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N-acetoxy-2-acetylaminofluorene modification of a deoxyoligonucleotide duplex.

The carcinogen N-acetoxy-2-acetylaminofluorene was reacted with d (CCACGCACC) to form a covalent adduct with attachment at the single guanine. The sample was purified, mixed 1:1 with d (GGTGCGTGG) and studied by thermal denaturation experiments. The Tm for the mixture was 35 +/- 3 degrees C, consist...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
I whakaputaina i:Nucleic Acids Res
Ngā kaituhi matua: Sanford, D G, Krugh, T R
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Oxford University Press 1985
Urunga tuihono:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC321921/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4034398/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/13.16.5907
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